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[13] DSS Model Results : Weight loss significantly reduced at day 8 Myeloperoxidase activity (neutrophil marker) dropped 50% Prevented colon weight increase and length decrease IL-6 and IL-12 mRNA expression significantly reduced Histology showed less inflammation, reduced cell damage, fewer inflammatory cells in tissue layers TNBS Model Results (more acute inflammation): Weight loss reduced within 1-2 days post-TNBS Colonic MPO activity decreased 30% Prevented TNBS-induced colon shortening Broad cytokine suppression: IL-1, IL-6, TNF-, IFN- mRNA all reduced KPV didnt affect inflammatory markers in healthy mice

If you have patient with unexpected macrocytic anaemia and call the lab to ask to add on b12, they will laugh and inform you that the sample has to be very fresh

Recording daily symptom severity, medication use, food tolerance, and sleep quality creates a useful baseline for comparison

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doi:10.1007/s00394-020-02454-3 Read SA, Obeid S, Ahlenstiel C, Ahlenstiel G

At Simply Clinics, we recognise the emotional and physical toll conditions like Bells Palsy can take